Common prostate cancer medications may be less safe than previously thought

Men taking either of the two most common oral medications for advanced prostate cancer who had also undergone hormone therapy to treat their disease were at higher risk of serious metabolic or cardiovascular issues than patients who were only receiving hormone therapy, researchers found.

New research may explain unexpected effects of common painkillers

Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin are widely used to treat pain and inflammation. But even at similar doses, different NSAIDs can have unexpected and unexplained effects on many diseases, including heart disease and cancer.

Insomnia in midlife may manifest as cognitive problems in retirement age

According to a new study, long-term insomnia symptoms can pose a risk of poorer cognitive functioning later in life. This is another reason why insomnia should be treated as early as possible.

If you take several medications, ‘polypharmacy’ is a word to know

Here’s a scenario so common that it applies to nearly 92 percent of older adults with cancer: An individual comes in for treatment and reports taking several medications that might include a drug for high blood pressure or heart disease, an antidepressant, or something for diabetes. The person may also take frequent doses of a headache pill, over-the-counter pills to relieve heartburn or reflux, antihistamines, and vitamins and minerals. But, patients may not report these as often to the medical team.

New tool to create hearing cells lost in aging

‘We have overcome a major hurdle’ to restore hearing.  Hearing loss due to aging, noise and certain cancer drugs has been irreversible, because scientists have not been able to reprogram existing cells to develop into the outer and inner ear sensory cells — essential for hearing — once they die. But scientists now have discovered a single master gene that programs ear hair cells into either outer or inner ones, overcoming a major hurdle that had prevented the development of these cells to restore hearing.

Combining certain meds with ibuprofen can permanently injure kidneys

Commonly prescribed hypertension drugs may be harmful in combination with ibuprofen. Anyone who is taking a diuretic and a renin-angiotensin system (RSA) inhibitor for high blood pressure should be cautious about also taking ibuprofen, according to new research.

Old skins cells reprogrammed to regain youthful function

Scientists have developed a new technique for rejuvenating skin cells. This technique has allowed researchers to rewind the cellular biological clock by around 30 years according to molecular measures, significantly longer than previous reprogramming methods. The partially rejuvenated cells showed signs of behaving more like youthful cells in experiments simulating a skin wound. This research, although in early stages, could eventually have implications for regenerative medicine, especially if it can be replicated in other cell types.

Starting screening before age 50 is found to significantly reduce the risk and incidence of colorectal cancer in women

A new study reports a 50 to 60 percent lower risk of colorectal cancer (CRC) among women who started endoscopy screening at age 45 compared to those who had not undergone screening at all.

Fecal transplants reverse hallmarks of aging

In the search for eternal youth, fecal transplants may seem like an unlikely way to reverse the aging process. However, scientists have provided evidence, from research in mice, that transplanting fecal microbiota from young into old mice can reverse hallmarks of aging in the gut, eyes, and brain. In the reverse experiment, microbes from aged mice induced inflammation in the brain of young recipients and depleted a key protein required for normal vision. These findings show that gut microbes play a role in the regulating some of the detrimental effects of ageing and open up the possibility of gut microbe-based therapies to combat decline in later life.

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